Drug Uses Citalopram is used for treating depression. It may also be used for other conditions as determined by your doctor. How to use Use Citalopram as directed by your doctor. Drug Class and Mechanism Citalopram is a selective serotonin reuptake inhibitor (SSRI). It works by restoring the balance of serotonin, a natural substance in the brain, which helps to improve certain mood problems. Missed Dose If you miss a dose of Citalopram, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Storage Store Citalopram at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Citalopram out of the reach of children and away from pets.