Drug Uses Effexor XR being a potent inhibitor of the reuptake of norepinephrine and serotonin, two neurotransmitters which seek to play an important role in the pathophysiology of depression. Signs of depression can be relieved by a correction of the imbalance of the above mentioned two chemicals in your brain. Usage Following the dosage instructions of your doctor is the best way to use any medication. If you are unsure or do not remember the instructions then you may read the medicine label for more detailed information. You may choose to take Effexor XR with a meal. It is advisable not to chew or crush the capsule but if you want you can empty the content of the capsule in a spoon and swallow the whole. Please drink a full glass of water with Effexor XR. It is very important that you complete the dosage schedule and do not interrupt it in between without seeking prior consultation from your doctor. Taking your medication at the same time each day is a tried and tested method to avoid missing any doses. Missed Dose Despite your best attempts at remembering, if you still miss out on a dose, then take it as soon as you remember about it. But keep in mind that you will have to adjust your next dose by spacing it out by 4 to 5 hours. If this is not possible, then the best thing to do would be to skip the missed dose and continue with your normal dosage schedule. Never try to compensate for the missed dose by taking a double dose together. It may cause adverse effects. Storage Store Effexor XR at room temperature preferably between 20 to 25 degrees C. Always keep it in a cool dark place that is not directly exposed to sources of heat or moisture and sunlight. Protect it from kids and pets.