Drug Uses Sinequan is used for treating depression or anxiety in certain patients. It may also be used for other conditions as determined by your doctor. How to use Use Sinequan as directed by your doctor. Check the label on the medicine for exact dosing instructions. Sinequan comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Sinequan refilled. Take Sinequan by mouth with or without food. Taking Sinequan at bedtime may help reduce side effects (eg, daytime drowsiness). Discuss this possibility with your doctor. Drug Class and Mechanism Sinequan is a tricyclic antidepressant. It is not known exactly how it works. It may increase the activity of certain chemicals in the brain, which help elevate mood. Missed Dose If you miss a dose of Zyvox, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Storage Sinequan should be stored below 86 degrees F (30 degrees C) in a tight, light resistant container.