Drug Uses ZOFRAN is very useful in treating nausea and vomiting that may be caused by surgery or by medicine to treat cancer (chemotherapy or radiation) and it works by blocking a chemical thought to be a cause of nausea and vomiting in certain situations (e.g., chemotherapy). Usage Following the dosage instructions of your doctor is the best way to use any medication. If you are unsure or do not remember the instructions then you may read the medicine label for more detailed information. You may choose to take ZOFRAN with a meal or with antacid in order avoid acidity. Please drink a full glass of water with ZOFRAN. It is very important that you complete the dosage schedule and do not interrupt it in between without seeking prior consultation from your doctor. Taking your medication at the same time each day is a tried and tested method to avoid missing any doses. Drug Class and Mechanism ZOFRAN falls under serotonin 5-HT3 receptor blocker and it works by blocking a chemical thought to be a cause of nausea and vomiting in certain situations (e.g., chemotherapy). Missed Dose Despite your best attempts at remembering, if you still miss out on a dose, then take it as soon as you remember about it. But keep in mind that you will have to adjust your next dose by spacing it out by 4 to 5 hours. If this is not possible, then the best thing to do would be to skip the missed dose and continue with your normal dosage schedule. Never try to compensate for the missed dose by taking a double dose together. It may cause adverse effects. Storage Store ZOFRAN at room between 68 and 77 degrees F(20 and 25 degrees C).. Always keep it in a cool dark place that is not directly exposed to sources of heat or moisture and sunlight. Protect it from kids and pets.